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OCR: in, is The structure of the TSH-R, o glycoprot shown in Fig. 17.10 in diagrammatic for ith Graves'TSH and TSH-R antibodies in patients v of the disease bind to the extracellular domain hked receptor, and by acting via the receptor-1 production G-binding protein stimulate cyclic AMP sis. and subsequent thyroid hormone synth sy of Modified from McGregor (1992) by cour Oxford University Press.